About a hundred Uganda kobs were transferred into the park from Murchison Falls. There are also plans to reintroduce white rhino in the future. Kidepo is home to many animal species found nowhere else in the country, including cheetah, caracal, aardwolf, greater and lesser kudu, mountain reedbuck and Guenther’s dik-dik. Although primarily a savannah reserve, five primate species are present, including the rare and localized patas monkey. The endangered Rothschild’s giraffe is present with five young ones.

The park harbors a great diversity of animal species than other parks. Of the 80 species of mammals listed, 28 are not found in any other Ugandan park. Among the Carnivore species unique to Kidepo region include the bat-eared fox, striped hyena, aardwolf, caracal, cheetah and hunting dog. Striped Hyena, Lesser Kudu, Grant’s Gazelle and Beisa Oryx have not been seen at all in recent times and are presumed to be locally extinct.

Elephant, burchell’s zebra, bush pig, warthog, rothschild giraffe, cape buffalo, eland, bush buck, bush duskier, defassa water buck, bohor reed buck, jackson’s hartbeest and oribi are some of the other large game herds as well as; lion, zebra, leopard, Buffalo, several small cats, Kangoni, spotted hyena, black-backed jackal and side-striped jackal are commonly seen.

Five species of primate are found in the park the Kavirondo bush baby being endemic. Oribis are abundant in the Narus Valley, whilst the dry thorn thickets in the north are home to Guenther’s Dik. Senegal Galago may be found in the rest camp at night and the common White-tailed Mongoose but are more likely to be found on a night drive.